Get 1-Pentyl-3-(1-naphthoyl)indole – Buy JWH-018 – CAS 209414-07-3 – Order Legal Highs
$210.00 – $5,300.00
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Highlights:
JWH-018 (also called AM-678 and 1-Pentyl-3-(1-naphthoyl)indole) is orally active when dissolved in a lipid, which can increase the duration significantly. It is a full agonist synthetic cannabinoid first synthesized by organic chemist John W. Huffman. Like other cannabinoids, JWH-018 is commonly smoked or vaporized to achieve a quick onset of effects and rapid offset.
Description
In vitro studies show that JWH-018 binds to the brain cannabinoid receptor CB1 with increased affinity relative to Δ9-THC and displays agonist properties in functional assays, suggesting that it would have the same effects as Δ9-THC in vivo. In drug discrimination studies in rats, JWH 018 generalized to Δ9-THC, i.e. produced subjective effects
Behavioral pharmacology studies show that JWH-018 has Δ9-THC-like activity in animals. In mice, it decreases overall activity, produces analgesia, decreases body temperature and produces catalepsy. Together, these four effects are used by scientists to predict Δ9-THC-like psychoactivity in humans. AM-678 activity in all four tests
Additional information
Quantity | 10g, 50g, 200g, 500g |
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