Tiletamine HCl belongs to the cyclohexamine group of dissociative agents and zolazepam is a benzodiazepine related to diazepam and midazolam. The combination is manufactured as a lyophilized powder that can be added to water, saline or 5% dextrose for reconstitution. The resulting solution is clear with a pH of 2.0–3.5.
JWH-018 (also called AM-678 and 1-Pentyl-3-(1-naphthoyl)indole) is orally active when dissolved in a lipid, which can increase the duration significantly. It is a full agonist synthetic cannabinoid first synthesized by organic chemist John W. Huffman. Like other cannabinoids, JWH-018 is commonly smoked or vaporized to achieve a quick onset of effects and rapid offset.
Isotonitazene Powder is a benzimidazole derived opioidanalgesic drug related to etonitazene, which has been sold as a designer drug. Isotonitazene Powder has only around half the potency of etonitazene in animal studies, but it is likely even less potent in humans as was seen with etonitazene (1000 times as potent as morphine in animal models yet only 60 times as potent in humans).
Zolazepam is a pyrazolodiazepinone derivative used as an anaesthetic in veterinary medicine. Zolazepam is typically used in combination with the NMDA antagonist tiletamine or the α2 adrenoceptor agonist xylazine. It is around four times the potency of diazepam but it is both water-soluble and un-ionized at physiological pH meaning that its onset is very fast.
Flualprazolam is a high potency triazolo-benzodiazepine with sedative effects similar to other benzodiazepines. Flualprazolam, a fluorinated analog of alprazolam, is an emerging designer benzodiazepine with increasing prevalence, which is an example of a modification to a prescribed benzodiazepine.
Nembutal Sodium (Pentobarbital Pills) is a barbiturate (bar-BIT-chur-ate). This medicine slows the activity of your brain and nervous system. Nembutal (Pentobarbital Sodium) is used short-term as a sedative to treat insomnia, or to cause you to fall asleep for surgery. This medicine is also used as an emergency treatment for seizures.
Xylazine Hydrochloride is a thiazine derivative used in veterinary medicine as the hydrochloride for sedation, analgesia, muscle relaxation and for anaesthetic premedication. It is available as 2% injectable solution and as a dry substance with solvent for intravenous or intramuscular injection.
Bromazolam Powder (Chemical Abstracts Service [CAS] registry number: 71368-80-4; CAS name: 8-bromo-1-methyl6-phenyl-4H-S-triazolo[4,3-a][1,4]benzodiazepine) is a triazolobenzodiazepine that was originally developed as a candidate medication but was never approved for use.