Purchase Bromazolam Powder – Buy XLI-268 Powder – Order CAS 71368-80-4


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Bromazolam Powder (Chemical Abstracts Service [CAS] registry number: 71368-80-4; CAS name: 8-bromo-1-methyl6-phenyl-4H-S-triazolo[4,3-a][1,4]benzodiazepine) is a triazolobenzodiazepine that was originally developed as a candidate medication but was never approved for use.


Bromazolam Powder is a triazolo-benzodiazepine structurally related to the internationally controlled substance alprazolam in which the chlorine atom is replaced by a bromine atom. Bromazolam is also structurally related to flubromazepam, from which it differs by the lack of a fluorine at the 2-position of the phenyl ring. Bromazolam is also structurally similar to pyrazolam, whereby the pyridinyl group has been replaced by a phenyl group.

What is Bromazolam Powder?

Monohydroxylated metabolites include 4-hydroxylated bromazolam and a-hydroxy bromazolam, with an additional dehydroxylated metabolite, a-5-dihydroxy-bromazolam. After glucuronidation, a-hydroxy glucuronide and N-glucuronide are the most abundant phase II metabolites. Information on the compound’s pharmacodynamics is confined to a single in-vitro study of its binding to a-subunits of the a-aminobutyric acid type A/benzodiazepine receptor complex. Bromazolam was nonselective for  a-subunits, showing measurable binding affinity at receptors containing a-1 (Ki = 2.8 nM), a-2 (Ki = 0.69 nM) and a-5 (Ki = 0.62 nM) subunits.

Effects of Bromazolam Powder?

Bromazolam is sold as tablets or powders under its own name or as XLI-268 (1). Novel psychoactive substances (NPS) belonging to the benzodiazepines class can be purchased mainly on the drug online market under various street names, such as “legal benzodiazepines”, “designer Benzodiazepine” and “research chemicals”. Bromazolam phase I metabolism is mediated primarily by several isoforms of the CYP450 enzyme system (CYP2B6, CYP2C19, CYP3A4, CYP3A5 and CYP2C9), whereas phase II metabolism involves the isoenzymes
UGT1A4 and UGT2810.

When to use Bromazolam Powder

Bromazolam is soluble in dimethylformamide at a concentration of 30 mg/mL, in dimethylsulphoxide at 20 mg/mL, in ethanol at 10 mg/mL, in methanol at 1 mg/mL and in a 1:1 mixture of dimethylformamide and phosphate-buffered saline (pH 7.2) at 0.5 mg/mL (4). Analytical methods for identification of bromazolam in seized sample matrices include IR,1H NMR, gas chromatography–MS and liquid chromatography–MS (9, 10).

Strongest Benzodiazepines sold Online

Synthetic bromazolam has been characterized by proton and carbon nuclear magnetic resonance (1H NMR and 13C NMR), mass spectrometry (MS) and infra-red spectroscopy (IR) (3). Bromazolam is available as a reference material from various commercial suppliers and is used in routine analysis for forensic and clinical investigations.

Best Triazolo-benzodiazepine Powder

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10g, 50g, 200g, 500g

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